Is Hyperbaric Oxygen the Answer for Concussion Treatment in Kids HEAD TOPICS

Is Hyperbaric Oxygen the Answer for Concussion Treatment in Kids

10/23/2022 2:23:00 AM

A small study showed strong benefits from the therapy even years after a brain injury but a leading concussion expert pushed back on the findings

Traumatic Brain İnjury Tbi Traumatic Brain İnjury

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Medscape

Hyperbaric oxygen therapy may help resolve symptoms of concussion in children years after they have suffered a brain injury, researchers in Israel have found. A small study showed strong benefits from the therapy even years after a brain injury but a leading concussion expert pushed back on the findings The researchers assessed 17 of the participants' baseline cognitive and behavioral function scores (eight children who were younger than 10 were deemed too young to undergo baseline testing). The researchers then randomly assigned 15 participants to receive daily sessions of hyperbaric oxygen therapy for 2 months, and 10 to a sham treatment ― a placebo design the researchers called novel. MRI scans of eight patients in the therapy group and eight in the sham group showed that among the patients who underwent hyperbaric oxygen therapy, brain tissue density was increased, which the researchers correlated with gains in cognition and motor skills. Read more:
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Researchers at the Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center and their colleagues enrolled 25 children and adolescents aged 8 to 15 years in the randomized, controlled trial. All of the participants had persistent post-concussion syndrome after experiencing a traumatic brain injury 6 to 10 years before enrolling in the trial. Jones’ 25-year-old gal pal, Alexis Thone, and Gabriel’s younger brother, who is 21, were also found in distress, but saved by Narcan, according to authorities. The researchers assessed 17 of the participants' baseline cognitive and behavioral function scores (eight children who were younger than 10 were deemed too young to undergo baseline testing). The plane was headed to Henderson, Nevada when it went off the radar in a remote area of Seligman , which is between Kingman and Flagstaff. The researchers then randomly assigned 15 participants to receive daily sessions of hyperbaric oxygen therapy for 2 months, and 10 to a sham treatment ― a placebo design the researchers called novel. The Missouri State Highway Patrol will test the substance. "We have accomplished many incredible firsts in this study, including a unique sham protocol which is the first of its kind in hyperbaric medicine," Amir Hadanny, MD, chief researcher at the Sagol Center and lead author of the study, said in a written statement. He insists his firm is helping clients get safely into and out of stores, and will continue to fight for them. "The protocol enables true masking and blinding of patients without any active treatment. Pike County Missouri Sheriff Jones is accused of attempting “to destroy, suppress and conceal physical evidence” by tossing out narcotics test kits in a dumpster before deputies arrived, according to the probable cause statement. An uninvolved airplane in the accident area reported "serious moderate turbulence" and security video showed heavy rain and gusty wind conditions at the time of the crash, according to the NTSB report." Patients who underwent hyperbaric oxygen therapy experienced as much as a 12% improvement from baseline in their scores on tests of memory, cognition, and motor skills, compared to those who received sham treatment. Among the participants who received sham treatment, symptoms improved by 2%. Pike County Missouri Sheriff The lawman was taken into custody during a traffic stop Wednesday afternoon and held on $150,000 cash-only bail. MRI scans of eight patients in the therapy group and eight in the sham group showed that among the patients who underwent hyperbaric oxygen therapy, brain tissue density was increased, which the researchers correlated with gains in cognition and motor skills. Texas couple killed in plane crash west of Flagstaff The Coconino County Medical Examiner identified the victims as 42-year-old Chad Wilson and Brandi Wilson, 42. Images of the brains after surgery suggest improvement in brain signaling and growth of new cells, according to Mohammed Elamir, MD, lead physician at AVIV Clinics, in The Villages, Florida. Alexis Thone was arrested on a second-degree drug trafficking and possession of controlled substance charges. who was not involved in the study. (Hadanny also is affiliated with AVIV. With Post wires.) "This [study] replicates what we already know is possible to do in the brain as a result of concussion and traumatic brain injury in adults, just applied to children," Elamir told Medscape Medical News . Dr Elizabeth Pieroth But Elizabeth M. Pieroth, PsyD, ABPP, MPH, director of the concussion program at Midwest Orthopaedics at Rush University Medical Center in Chicago, said the findings do not provide enough evidence to recommend hyperbaric oxygen treatment for post-concussion syndrome. "There are so many confounding variables here. It's hard to say that hyperbaric oxygen treatment was the cause of the improvement," Pieroth said. Pieroth said the researchers tried to capture a broad variety of conditions by including a small group of young patients whose symptoms ranged from mild to moderate in severity. The study did not provide information as to what caused each participant's post-concussion syndrome or whether they had previously undergone other treatments for their symptoms. Six to 10 years"is very far out from the event," she said. "Maybe those kids didn't have the right [initial] treatment based on what caused their injury." The most common side effects reported from patients in both arms of the study were mild ear pain and inflamed ear tubes. Elamir said the finding adds to the growing evidence on the benefits of hyperbaric oxygen therapy to help treat traumatic brain injury and prevent further physical, psychological, and cognitive deterioration. "The sooner we act, the more difference we can make at an earlier point," he said. Pieroth disagreed, saying that hyperbaric oxygen therapy is not a primary treatment or replacement for the standard of care for children and adults with post-concussion syndrome ― time and tailored management of patients' symptoms. The number of therapy sessions the researchers used in the study to possibly achieve their outcome ― daily hourlong sessions conducted five times per week for 60 days ― is not possible for many children. "That's so unrealistic in clinical use," said Pieroth, who noted that in Chicago, the cost of the"unproven" therapy would be roughly $8000. "I have always said to people, 'I want [hyperbaric oxygen therapy] to work;' I really desperately want my patients to feel better," Pieroth added."I would scream it from the rooftop if it works, but the data doesn't support it. This article just doesn't change my opinion. " Elamir and Pieroth reported no relevant financial relationships. Hadanny works for AVIV Scientific LTD. Sci Rep. .