Publications - Underhill Lab Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Underhill Lab Back to Underhill Lab Lab Members Publications Research Areas Publications See a complete PubMed list of publications by David Underhill, PhD. Selected Key Publications Wheeler ML, Limon JJ, Underhill DM. Immunity to commensal fungi: detente and disease. Annu Rev Pathol. 2017 Jan 24;12:359-385. http://www.annualreviews.org/doi/abs/10.1146/annurev-pathol-052016-100342. Wolf AJ, Liu GY, Underhill DM. Inflammatory properties of antibiotic-treated bacteria. J Leukoc Biol. 2017 Jan;101(1):127-134. https://jlb.onlinelibrary.wiley.com/doi/10.1189/jlb.4MR0316-153RR. Wolf AJ, Reyes CN, Liang W, Becker C, Shimada K, Wheeler ML, Cho HC, Popescu NI, Coggeshall KM, Arditi M, Underhill DM. Hexokinase is an innate immune receptor for the detection of bacterial peptidoglycan. Cell. 2016 Jul 28;166(3):624-636. http://www.cell.com/cell/fulltext/S0092-8674(16)30723-1. Wheeler ML, Limon JJ, Bar AS, Leal CA, Gargus M, Tang J, Brown J, Funari VA, Wang HL, Crother TR, Arditi M, Underhill DM, Iliev ID. Immunological consequences of intestinal fungal dysbiosis. Cell Host Microbe. 2016 Jun 8;19(6):865-873. http://www.cell.com/cell-host-microbe/fulltext/S1931-3128(16)30199-8. Underhill DM, Pearlman E. Immune interactions with pathogenic and commensal fungi: a two-way street. Immunity. 2015 Nov 17;43(5):845-858. http://www.cell.com/immunity/fulltext/S1074-7613(15)00448-3. Müller S, Wolf AJ, Iliev ID, Berg BL, Underhill DM, Liu GY. Poorly cross-linked peptidoglycan in MRSA due to mecA induction activates the inflammasome and exacerbates immunopathology. Cell Host Microbe. 2015 Nov 11;18(5):604-612. http://www.cell.com/cell-host-microbe/fulltext/S1931-3128(15)00421-7. Underhill DM, Iliev ID. The mycobiota: interactions between commensal fungi and the host immune system. Nat Rev Immunol. 2014 Jun;14(6):405-416. http://www.nature.com/nri/journal/v14/n6/full/nri3684.html. Ma J, Becker C, Reyes C, Underhill DM. Cutting edge: FYCO1 recruitment to dectin-1 phagosomes is accelerated by light chain 3 protein and regulates phagosome maturation and reactive oxygen production. J Immunol. 2014 Feb 15;192(4):1356-1360. http://www.jimmunol.org/content/192/4/1356. Iliev ID, Funari VA, Taylor KD, Nguyen Q, Reyes CN, Strom SP, Brown J, Becker CA, Fleshner PR, Dubinsky M, Rotter JI, Wang HL, McGovern DPB, Brown GD, Underhill DM. Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis. Science. 2012;336(6086):1314-1317. http://www.sciencemag.org/content/336/6086/1314. Kaplan A, Ma J, Kyme P, Wolf AJ, Becker CA, Tseng CW, Liu GY, Underhill DM. Failure to induce interferon-beta production during Staphylococcus aureus infection contributes to pathogenicity. J Immunol. 2012;189(9):4537-4545. http://www.jimmunol.org/content/189/9/4537.full. Ma J, Becker C, Lowell CA, Underhill DM. Dectin-1-triggered recruitment of light chain 3 protein to phagosomes facilitates major histocompatibility complex class II presentation of fungal-derived antigens. J Biol Chem. 2012 Oct 5;287(41):34149-34156. http://www.jbc.org/content/287/41/34149. Underhill DM, Goodridge HS. Information processing during phagocytosis. Nat Rev Immunol. 2012 Jul 1;12:492-502. http://www.nature.com/nri/journal/v12/n7/execsumm/nri3244.html. Wolf AJ, Arruda A, Reyes CN, Kaplan AT, Shimada T, Shimada K, Arditi M, Liu G, Underhill DM. Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria. J Immunol. 2011;187(11):6002-6010. http://www.jimmunol.org/content/187/11/6002. Goodridge HS, Reyes CN, Becker CA, Katsumoto TR, Ma J, Wolf AJ, Bose N, Chan A, Magee AS, Danielson ME, Weiss A, Vasilakos JP, Underhill DM. Activation of the innate immune receptor Dectin-1 upon formation of a "phagocytic synapse." Nature. 2011;472(7344):471-475. http://www.nature.com/nature/journal/v472/n7344/full/nature10071.html. Shimada T, Park B, Wolf AJ, Brikos C, Goodridge HS, Becker CA, Reyes CN, Miao EA, Aderem A, Götz F, Liu GY, Underhill DM. Staphylococcus aureus evades the lysozyme-based digestion of peptidoglycan that links phagocytosis and macrophage IL-1 secretion. Cell Host and Microbe. 2010;7(1):38-49. http://www.cell.com/cell-host-microbe/abstract/S1931-3128(09)00418-1. Contact the Underhill Lab 8700 Beverly Blvd. Davis Building, Room 4094F Los Angeles, CA 90048 310-423-7654 Send A Message Please ensure Javascript is enabled for purposes of website accessibility