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DNA methylation loss in late-replicating domains is linked to mitotic cell divisions. Nat Genet. 2018 Apr 2;50(4):591-602. Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, et al. Asparagine bioavailability governs metastasis in a model of breast cancer. Nature. 2018 Feb 15;554(7692):378-381. Lin DC, Dinh HQ, Xie JJ, Mayakonda A, Silva TC, Jiang YY, Ding LW, He JZ, Xu XE, Hao JJ, Wang MR, Li C, Xu LY, Berman BP, Koeffler HP. Identification of distinct mutational patterns and new driver genes in oesophageal squamous cell carcinomas and adenocarcinomas. Gut. 2017 Aug 31. pii: gutjnl-2017-314607. de Couto G, Gallet R, Cambier L, Jaghatspanyan E, Makkar N, Dawkins J, Berman BP, Marbán E. Exosomal microRNA transfer into macrophages mediates cellular postconditioning. Circulation. 2017 Jul 11;136(2):200-214. Erard N, Knott SRV, Hannon GJ. A CRISPR resource for individual, combinatorial, or multiplexed gene knockout. Mol Cell. 2017 Jul 20;67(2):348-354.e3. Lin DC, Mayakonda A, Dinh HQ, Huang P, Lin L, Liu X, Ding LW, Wang J, Berman BP, Song EW, et al. Genomic and epigenomic heterogeneity of hepatocellular carcinoma. Cancer Res. 2017 May 1;77(9):2255-2265. Adler EK, Corona RI, Lee JM, Rodriguez-Malave N, Mhawech-Fauceglia P, Sowter H, Hazelett DJ, Lawrenson K, Gayther SA. The PAX8 cistrome in epithelial ovarian cancer. Oncotarget. 2017 Nov 27;8(65):108316-108332. Yáñez A, Coetzee SG, Olsson A, Muench DE, Berman BP, Hazelett DJ, Salomonis N, Grimes HL, Goodridge HS. Granulocyte-monocyte progenitors and monocyte-dendritic cell progenitors independently produce functionally distinct monocytes. Immunity. 2017 Nov 21;47(5):890-902. Phelan C, Kuchenbaeker KB, Tyrer JP, Kar S, Lawrenson K, Winham SJ, […], Hazelett DJ, Offit K, Simard J, Schmutzler RK, Monteiro AN, Couch FJ, Berchuck A, Chenevix-Trench G, Goode EL, Sellers TA, Gayther SA, et al. Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Nat Genet 2017 May;49(5):680-691. Conti DV, Wang K, Sheng X, Bensen JT, Hazelett DJ, Cook MB, Ingles SA, Kittles RA, Strom SS, Rybicki BA, et al. Two novel susceptibility loci for prostate cancer in men of African ancestry. J Natl Cancer Inst. 2017 Aug 1;109(8). Hao JJ, Lin DC, Dinh HQ, Mayakonda A, Jiang YY, Chang C, Jiang Y, Lu CC, Shi ZZ, Xu X, Zhang Y, Cai Y, Wang JW, Zhan QM, Wei WQ, Berman BP, Wang MR, Koeffler HP. Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma. Nat Genet. 2016 Dec;48(12):1500-1507. Lawrenson K, Kar S, McCue K, Kunchenbaeker K, Michailidou K, Tyrer J, Beesley J, Ramus SJ, Li Q, [...], Gayther SA. Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. Nat Commun. 2016 Sep 7:7:12675. Amos CI, Dennis J, Wang Z, Byun J, Schumacher FR, Gayther SA, Casey G, Hunter DJ, Sellers […], Hazelett DJ, et al. The OncoArray Consortium: a network for understanding the genetic architecture of common cancers. Cancer Epidemiol Biomarkers Prev. 2017 Jan;26;(1):126-135. Kar S, Adler E, Tyrer J, Hazelett D, Anton-Culver H, Bandera EV, Beckmann MW, Berchuck A, Bogdanova N, Brinton L, et al. Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci. Br J Cancer. 2017 Feb 14;116(4):524-535. Coetzee SG, Pierce S, Brundin P, Brundin L, Hazelett DJ, Coetzee GA. Enrichment of risk SNPs in regulatory regions implicate divere tissues in Parkinson’s disease etiology. Sci Rep. 2016 Jul 27;6:30509. Have Questions or Need Help Contact us if you have questions, or wish to learn more about bioinformatics and functional genomics research at Cedars-Sinai. 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