Urinary Tract Infections UTIs in Older Adults Medications Nitrofur

Urinary Tract Infections UTIs in Older Adults Medications Nitrofur

Urinary Tract Infections (UTIs) in Older Adults, Medications, Nitrofur...

Can a UTI Drug Be Toxic

Yes some can so it may be wise to talk with your doctor about changing medications

Q: For several years I have been taking nitrofurantoin 100 mg to prevent recurring bladder and urinary tract infections (UTIs). I’m a 75-year-old woman and the medication has been effective, but I’ve read that it can build up at toxic levels in a person’s body. If this is true, is there a safer medication I could be using instead? A: As we age, our bodies lose some of their ability to process and clear the medications we take.

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For instance, the kidneys of an average 75-year-old are much less able to clear many types of drugs — including — because they’re functioning at only about half the efficiency of those of a young adult. That means nitrofurantoin can steadily accumulate in the body, which may cause serious side effects, including:
,
a worsening of existing respiratory problems, including (scarring of the lung tissue) and , both of which can be fatal (a form of anemia caused by the abnormal breakdown of red blood cells), which also can be fatal
I recommend that you speak with your physician about changing to (100 mg at bedtime). This drug will prevent infections just as well as the nitrofurantoin but without the same risk of adverse effects.
My other recommendations have nothing to do with drugs and are more about preventing urinary tract infections than treating them: Drink lots of water (at least 8 to 10 glasses a day). Avoid . Make sure you’re getting enough . Eat lots of blueberries and cranberries, or drink juices made from them. Both berries are loaded with , a natural bacteria-fighting compound that helps to ward off UTIs.

"Ask the Pharmacist" is written by Armon B. Neel Jr., PharmD, CGP, in collaboration with journalist Bill Hogan. They are co-authors of Are Your Prescriptions Killing You?, to be published next year by Atria Books.
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Ask the Pharmacist

Information contained in the column by is intended to help individuals and their families become more informed about medication usage and interactions, and be better health care consumers. Any advice or information provided should not be followed in lieu of a personal consultation with a trained medical professional. Cancel You are leaving AARP.org and going to the website of our trusted provider. The provider’s terms, conditions and policies apply. Please return to AARP.org to learn more about other benefits. Your email address is now confirmed. You'll start receiving the latest news, benefits, events, and programs related to AARP's mission to empower people to choose how they live as they age. You can also by updating your account at anytime. You will be asked to register or log in. Cancel Offer Details Disclosures

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