Chiefs vs. 49ers odds, line, spread, predictions: 2022 NFL picks, Week 7 best bets from model on 146-107 run - CBSSports.com site: media arena: nfl pageType: stories section: slug: chiefs-vs-49ers-odds-line-spread-predictions-2022-nfl-picks-week-7-best-bets-from-model-on-146-107-run sport: football route: article_single.us 6-keys: media/spln/nfl/reg/free/stories CBSSports.com 247Sports MaxPreps SportsLine Shop Play Golf Stubhub Caesars Sportsbook CBS Sports Home Sports HQ Fantasy NFL NCAA FB MLB Soccer NBA Golf NHL NCAA BB NCAA WBB Champions League MMA WWE Boxing NASCAR Motor Sports USFL NWSL WNBA Horse Racing Olympics Big3 Tennis High School WSOP Shop Promotions PBR 3Ice Stubhub Play Golf Play
Games
Play Now Football Pick em Play Now College Football Pick em View your Leagues Caesars Sportsbook
Fantasy Football
Football Pick em
College Pick em
Fantasy Baseball
Fantasy Basketball
Fantasy Hockey
Franchise Games
See All Sports Games Watch 7 Ole Miss at LSU
Paramount+ NCAA Football UEFA Champions League Serie A Liga Argentina Profesional Brasileirão NWSL Watch CBS Sports Network TV Shows & Listings Bet BET WITH CAESARS
BET FOOTBALL BET BASKETBALL BET BASEBALL BET HOCKEY BET GOLF BET FUTURES BET LIVE IN-GAME Podcasts Fantasy Football Today
Start or Sit (NFC Home Games) Nothing Personal with David Samson
Talking the business of sports Podcasts Home Fantasy Football Today NFL Pick Six Cover 3 College Football Eye On College Basketball Morning Kombat The First Cut Golf Log In My Teams Organize / See All Teams Help Account Settings Log Out Weekly Schedules NFL Power Rankings Stats Chiefs vs 49ers odds line spread predictions 2022 NFL picks Week 7 best bets from model on 146-107 run
SportsLine simulated San Francisco 49ers vs Kansas City Chiefs 10 000 times featuring Christian McCaffrey
By CBS Sports Staff Oct 22, 2022 at 10:04 am ET • 3 min read USATSI The Kansas City Chiefs (4-2) will travel to Levi's Stadium to play the San Francisco 49ers (3-3) on Sunday. Both clubs were handed losses in Week 6. The Chiefs couldn't outmatch the Buffalo Bills, falling 24-20. San Francisco went on the road to play the Atlanta Falcons, dropping that contest 28-14. The Niners made a splash on Thursday, acquiring two-time All-Pro running back Christian McCaffrey from the Carolina Panthers for several draft picks. McCaffrey could make his debut on Sunday, though the team hasn't confirmed its plans yet. Kickoff is set for 4:25 p.m. ET. Kansas City is a one-point favorite in the latest Chiefs vs. 49ers odds from Caesars Sportsbook, and the over/under is 49. Before making any 49ers vs. Chiefs picks, you need to check out the NFL predictions and betting advice from the SportsLine Projection Model. The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 7 of the 2022 NFL season on an incredible 146-107 run on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick em players four times during that span. Anyone who has followed it is way up. Now, the model has set its sights on Chiefs vs. Niners, and just locked in its picks and NFL predictions. You can visit SportsLine now to see the model's picks. Here are the NFL odds and betting lines for Niners vs. Chiefs:Chiefs vs. 49ers spread: Kansas City -1Chiefs vs. 49ers over/under: 49 pointsChiefs vs. 49ers money line: San Francisco +105, Kansas City -125KC: Over is 6-1 in Chiefs' last seven road gamesSF: 49ers are 6-0 ATS versus teams with a winning recordChiefs vs. 49ers picks: See picks at SportsLine Featured Game San Francisco 49ers vs. Kansas City Chiefs Moneyline Spread Total SF +100 BET NOW +1 -110 BET NOW o49 -110 BET NOW KC -120 BET NOW -1 -110 BET NOW u49 -110 BET NOW Why the Chiefs can cover
The Chiefs are ranked sixth in total offense (382.3) and fourth in passing yards per game (275.8). Kansas City dropped 30-plus points in three of its six games thus far. Quarterback Patrick Mahomes will be leading the offense into battle. Mahomes is a big-armed signal caller who has the talent to make top-notch throws. The four-time Pro Bowl selection can sling the football around with unorthodox arm angles. Mahomes is third in the league in passing yards (1,736) and tied for first in passing touchdowns (17). Last week, he tossed 338 yards with two passing touchdowns and two interceptions. See which team to back here. Why the 49ers can cover
While the Niners hope McCaffrey can give them a boost on offense, San Francisco has already showcased its ability to play strong defense. The 49ers play with a combination of discipline, aggression and speed. They are forcing their opponents into difficult situations and are thriving on that. The unit is first in the league in total defense (255.8) and second in passing yards allowed (168.3) and rushing yards allowed (87.5). Linebackers Dre Greenlaw and Fred Warner form a dynamic duo in the middle of the field. Greenlaw is an athletic and speedy playmaker who is instinctive against the run. The Arkansas product is leading the team in total tackles (55) along with three tackles for loss. Warner brings another agile difference-maker who can play great against the pass and run. The 2020 Pro Bowl selection is second on the team in total stops (44) with two pass deflections and 0.5 sacks. See which team to back here. How to make 49ers vs Chiefs picks
SportsLine's model is leaning Under on the point total. In fact, it's calling for 47 total points. It also says one side of the spread cashes well over 50% of the time. You can only see the model's pick at SportsLine. So who wins Niners vs. Chiefs? And which side of the spread cashes well over 50% of the time? Visit SportsLine now to see which side of the 49ers vs. Chiefs spread to jump on, all from the advanced model that is up almost $7,000 on NFL picks, and find out. Our Latest Stories
Report Magic Johnson in talks to own part of Raiders
Steven Taranto • 1 min read
Report Micah Parsons Trevon Diggs receive fines
Jordan Dajani • 1 min read
Report Teams expecting Chase Claypool to be available
Jordan Dajani • 1 min read
NFL Week 7 expert picks best bets more
Tyler Sullivan • 11 min read
Russell Wilson ruled out vs Jets Brett Rypien starts
Jonathan Jones • 1 min read
Report Texans to place Jonathan Greenard on IR
Jordan Dajani • 1 min read
Watch Now: Chiefs vs 49ers odds spread predictions NFL picks
CBS Sports Staff 3 min read NFL Week 7 expert picks best bets for every game
Tyler Sullivan 11 min read CMC trade grades for 49ers and Panthers
Josh Edwards 2 min read Brinson s picks Jags cool red-hot Giants
Will Brinson 10 min read McCaffrey in Niners O Wild stuff ahead
Jared Dubin 4 min read Prisco s picks Boys roll in Dak s return
Pete Prisco 6 min read Russell Wilson ruled out vs Jets Brett Rypien starts
Jonathan Jones 1 min read Week 7 injuries Colts Taylor expected in Giants WRs out
Bryan DeArdo 9 min read Report Teams expecting Claypool to be available
Jordan Dajani 1 min read Report Ravens Dobbins to have surgery out 4-6 weeks
Bryan DeArdo 1 min read