S. Wang Research Lab Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory S Wang Lab Cell-based therapy for retinal degeneration and optic nerve neuropathy The primary goal of our lab is to understand and develop treatments for degenerative retinal diseases. Ray Lund, PhD, a pioneer in the field, started using cell-based therapy for retinal degeneration over two decade ago; our current program expands our research to study optic nerve neuropathy and Alzheimer’s disease as well. We have been using stem cell therapy to slow down the progression of retinal degeneration and limit the development of the secondary vascular pathology. Our preclinical studies have led to three clinical trials using stem cells to treat macular degeneration. The Wang Laboratory is affiliated with the Regenerative Medicine Institute and Department of Biomedical Sciences. Breakthrough Research Areas Development of noninvasive cell-based therapy for retinal degeneration and associated vascular pathology Cell-based therapy for traumatic optic neuropathy Combined local and global cellular therapies to treat retinal degeneration Functional evaluation of vision Collaborations & Resources Collaborations Internal Board of Governors Regenerative Medicine Institute Smidt Heart Institute Department of Biomedical Sciences Van Eyk Laboratory External Institute of Ophthalmology and Visual Science, Rutgers, New Jersey Medical School Resources DAVID - Bioinformatics Database Smidt Heart Institute Van Eyk Laboratory Retina by John Dowling The Retinal Pigment Epithelium: Function and Disease by Michael F. Marmor and Thomas J. Wolfensberger GraphPad Prism S. Mark Taper Foundation Imaging Center Meet Our Team Learn more about the scientists, faculty members, investigators and other healthcare professionals of the S Wang Laboratory, whose dedicated efforts lead to groundbreaking discoveries. View Our Team Publications Human iPSC-Derived Neural Progenitors Preserve Vision in an AMD-Like Model. Tsai Y, Lu B, Bakondi B, Girman S, Sahabian A, Sareen D, Svendsen CN, Wang S. Stem Cells. 2015;33(8):2537-2549. A subsequent human neural progenitor transplant into the degenerate retina does not compromise initial graft survival or therapeutic efficacy. Lu B, Lin Y, Tsai Y, Girman S, Adamus G, Jones MK, Shelley B, Svendsen CN, Wang S. Transl Vis Sci Technol. 2015;4(1):7. Ocular changes in TgF344-AD rat model of Alzheimer's disease. Tsai Y, Lu B, Ljubimov AV, Girman S, Ross-Cisneros FN, Sadun AA, Svendsen CN, Cohen RM, Wang S. Invest Ophthalmol Vis Sci. 2014;55(1):523-534. Contact the S Wang Lab 8700 Beverly Blvd. Advanced Health Sciences Pavilion, Eighth Floor Los Angeles, CA 90048 Lab 310-248-8567 Office 310-248-7970 Send A Message Please ensure Javascript is enabled for purposes of website accessibility