Rutishauser Research Lab Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Rutishauser Lab The Rutishauser Laboratory at Cedars-Sinai is investigating the neural mechanisms of learning, memory and decision-making level of single neurons and networks thereof. We are a systems neuroscience laboratory and use a combination of in-vivo, single-unit electrophysiology in humans, intracranial electrocorticography, eye tracking, electrical stimulation, behavior and computational, and theoretical approaches. We have helped pioneer the technique of human single-neuron recordings and continue to advance the tools, methods and surgical techniques that allow such experiments. The Rutishauser Laboratory has an ongoing close collaboration with scientists at the California Institute of Technology. Our overarching goal is to capitalize on special neurosurgical situations to advance knowledge of the human nervous system. Our work is only possible because of a close collaboration between quantitative and experimental neuroscientists, neurologists and neurosurgeons—combining science and medicine. Work in the Rutishauser Laboratory is made possible by funding provided by the National Science Foundation, National Institutes of Health, Brain & Behavior Research Foundation and the McKnight Endowment Fund for Neuroscience. The Rutishauser Laboratory is located in the Department of Neurosurgery and the Maxine Dunitz Neurosurgical Institute and is also affiliated with the Neurology Department, the Center for Neural Science and Medicine, and the Department of Biomedical Sciences. Breakthrough Research Areas Learning and Memory Social Cognition Decision Making Methods Development Collaborations & Resources Internal Center for Neural Science and Medicine Jeffrey M. Chung, MD, FAAN Department of Biomedical Sciences Epilepsy Program Adam N. Mamelak, MD Movement Disorders Program Neurology & Neurosurgery Chrystal M. Reed, MD, PhD External Ralph Adolphs Laboratory, California Institute of Technology Richard Andersen Laboratory, California Institute of Technology Computation & Neural Systems Program, California Institute of Technology Katalin Gothard Laboratory, University of Arizona, Tucson Wolfram Schultz Laboratory, University of Cambridge Doris Tsao Laboratory, California Institute of Technology John O'Doherty Laboratory, California Institute of Technology Shuo Wang, Washington University in St. Louis Resources Software tools that we provide: OSort – spike sorting software package StimOMatic – closed-looped stimulus control NlxToMat – import of neurophysiology data into Matlab Datasets we provide: NWB – formatted single-neuron dataset during recognition memory Meet Our Team Learn more about the scientists and physicians of the Rutishauser Laboratory, whose dedicated efforts lead to groundbreaking discoveries. View Our Team Publications Distinct roles of dorsal and ventral subthalamic neurons in action selection and cancellation. Mosher CP, Mamelak AN, Malekmohammadi M, Pouratian N, Rutishauser U. Neuron. 2021 Mar 3;109(5):869-881.e6. Flexible recruitment of memory-based choice representations by the human medial frontal cortex. Minxha J, Adolphs R, Fusi S, Mamelak AN, Rutishauser U. Science. 2020 Jun 26;368(6498):eaba3313. Single-neuron correlates of error monitoring and post-error adjustments in human medial frontal cortex. Fu Z, Wu DJ, Ross I, Chung JM, Mamelak AN, Adolphs R, Rutishauser U. Neuron. 2019 Jan 2;101(1):165-177. Novelty-sensitive dopaminergic neurons in the human substantia nigra predict success of declarative memory formation. Kamiński J, Mamelak AN, Birch K, Mosher CP, Tagliati M, Rutishauser U. Curr Biol. 2018 May 7;28(9):1333-1343. Contact the Rutishauser Lab 127 S. San Vicente Blvd. Advanced Health Sciences Pavilion, 8th Floor Los Angeles, CA 90048 310-423-3277 Send A Message Please ensure Javascript is enabled for purposes of website accessibility