Pandol Research Lab Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Pandol Lab The Pandol Laboratory at the Cedars-Sinai Pancreatic Research Program is dedicated to establishing and maintaining the leading international research area at Cedars-Sinai for advancing the prevention, early diagnosis and treatment of pancreatic diseases. Pancreatic cancer, pancreatitis and diabetes are disorders with life-threatening consequences for patients and broad-reaching repercussions for their family members and friends. Each year pancreatic cancer is diagnosed in 250,000 patients worldwide (more than 40,000 in the U.S.), and because only a limited number of patients are diagnosed early enough for successful surgical intervention, 225,000 die. To date, chemotherapy and radiotherapy are only partially and transiently effective. Pancreatitis is life threatening in its acute stage and causes immense and painful suffering in its chronic stages. In the U.S., the number of hospital admissions for pancreatitis is greater than for any other gastrointestinal disease. The Pancreatic Research Program is dedicated to discovering and characterizing the disease mechanisms for pancreatitis so that effective treatments can be developed. Type 2 diabetes is a worldwide epidemic, with a prevalence reaching 10 percent in many populations. This is especially relevant to research in the Pandol Lab because diabetes underlies the risk of pancreatitis and pancreatic cancer, as well as other cancers and heart disease. Basic and translational research efforts at the Pancreatic Research Program are designed to advance clinical care delivery to our patients. The Pandol Laboratory is affiliated with the Pancreatic and Biliary Diseases Program and the Samuel Oschin Comprehensive Cancer Institute. Breakthrough Research Areas The Pandol Lab in the Cedars-Sinai Pancreatic Research Program is concentrating efforts to better understand the molecular mechanisms of pancreatic diseases and develop new prevention, diagnostic and effective treatments for these diseases. The Pancreatic Research Program's multidisciplinary team consists of molecular biologists, cell biologists, computational chemists, population scientists, clinical scientists and physicians, all working toward the common goal of enhanced treatments and outcomes for pancreatic cancer, pancreatitis and diabetes patients. Our research is focused on the following: Early diagnosis and disease prevention Signaling mechanisms, underlying risk factors and disease pathophysiology Development of novel therapeutics and enhanced treatments Human testing of new treatments Collaborations & Resources Collaborations Diabetes & Obesity Research Institute Digestive Diseases Research Center Endocrinology Research Samuel Oschin Comprehensive Cancer Institute Resources Microscopy and Cell Culture Chemistry and Biochemistry Animal Physiology and Human Biomedical Sample Preparation Molecular Biology and Physical Biochemistry Proteomics Specialized Reagents Access to Other Specialized Expertise and Equipment Computation and Structural Modeling Professional Societies View More Meet Our Team Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Pandol Laboratory, whose dedicated efforts lead to groundbreaking discoveries. View Our Team Publications New insights into the pathways initiating and driving pancreatitis. Gukovskaya AS, Pandol SJ, Gukovsky I. Curr Opin Gastroenterol. 2016 Jul 13. A bitter pill for type 2 diabetes? The activation of bitter taste receptor TAS2R38 can stimulate GLP-1 release from enteroendocrine L-cells. Pham H, Hui H, Morvaridi S, Cai J, Zhang S, Tan J, Wu V, Levin N, Knudsen B, Goddard WA 3rd, Pandol SJ, Abrol R. Biochem Biophys Res Commun. 2016 Jul 1;475(3):295-300. Prospective study of alcohol drinking, smoking, and pancreatitis: the multiethnic cohort. Setiawan VW, Pandol SJ, Porcel J, Wilkens LR, Le Marchand L, Pike MC, Monroe KR. Pancreas. 2016 Jul;45(6):819-825. Contact the Pandol Lab 110 N. George Burns Rd. Davis Building, Room 3096 Los Angeles, CA 90048 310-423-6082 Send a Message Please ensure Javascript is enabled for purposes of website accessibility