Publications - Guarnerio Lab Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Guarnerio Lab Back to Guarnerio Lab Lab Members Personal Statement Publications Research Areas Publications See a complete PubMed list of publications by Jlenia Guarnerio, PhD. Selected Key Publications Guarnerio J, Zhang Y, Cheloni G, Panella R, Katon JM, Simpson M, Matsumoto A, Papa A, Loretelli C, Petri A, et al. Intragenic antagonistic roles of protein and circRNA in tumorigenesis. Cell Res. 2019 Aug;29(8):628-640. https://www.nature.com/articles/s41422-019-0192-1. Mugoni V, Panella R, Cheloni G, Chen M, Pozdnyakova O, Stroopinsky D, Guarnerio J, Monteleone E, Lee JD, Mendez L, et al. Vulnerabilities in mIDH2 AML confer sensitivity to APL-like targeted combination therapy. Cell Res. 2019 Jun;29(6):446-459. https://www.nature.com/articles/s41422-019-0162-7. Guarnerio J, Mendez LM, Asada N, Menon AV, Fung J, Berry K, Frenette PS, Ito K, Pandolfi PP. A non-cell-autonomous role for PML in the maintenance of leukemia from the niche. Nat Commun. 2018 Jan 4;9(1):66. https://www.nature.com/articles/s41467-017-02427-x. German NJ, Yoon H, Yusuf RZ, Murphy JP, Finley LW, Laurent G, Haas W, Satterstrom FK, Guarnerio J, Zaganjor E, et al. PHD3 loss in cancer enables metabolic reliance on fatty acid oxidation via deactivation of ACC2. Mol Cell. 2016 Sep 15;63(6):1006-1020. https://www.cell.com/molecular-cell/fulltext/S1097-2765(16)30428-2. Guarnerio J, Bezzi M, Jeong JC, Paffenholz SV, Berry K, Naldini MM, Lo-Coco F, Tay Y, Beck AH, Pandolfi PP. Oncogenic role of fusion-circRNAs derived from cancer associated chromosomal translocations. Cell. 2016 Apr7;165(2):289-302. https://www.cell.com/cell/fulltext/S0092-8674(16)30276-8. Lunardi A, Varmeh S, Chen M, Taulli R, Guarnerio J, Ala U, Seitzer N, Ishikawa T, Carver BS, Hobbs RM, et al. Suppression of CHK1 by ETS family members promotes DNA damage response bypass and tumorigenesis. Cancer Discov. 2015 May;5(5):550-563. https://aacrjournals.org/cancerdiscovery/article/5/5/550/4891/Suppression-of-CHK1-by-ETS-Family-Members-Promotes Wei S, Kozono S, Kats L, Nechama M, Li W, Guarnerio J, Luo M, You MH, Yao Y, Kondo A, et al. Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer. Nat Med. 2015 May;21(5):457-466. https://www.nature.com/articles/doi:10.1038/nm.3839. Guarnerio J, Riccardi L, Taulli R, Maeda T, Wang G, Hobbs RM, Song MS, Sportoletti P, Bernardi R, Bronson RT, et al. A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells. Cancer Discov. 2015 Apr;5(4):396-409. https://aacrjournals.org/cancerdiscovery/article/5/4/396/4748/A-Genetic-Platform-to-Model-Sarcomagenesis-from Guarnerio J, Coltella N, Ala U, Tonon G, Pandolfi PP, Bernardi R. Bone marrow endosteal mesenchymal progenitors depend on HIF factors for maintenance and regulation of hematopoiesis. Stem Cell Reports. 2014 May 15;2(6):794-809. https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(14)00109-X. Coltella N, Percio S, Valsecchi R, Cuttano R, Guarnerio J, Ponzoni M, Pandolfi PP, Melillo G, Pattini L, Bernardi R. HIF factors cooperate with PML-RARα to promote acute promyelocytic leukemia progression and relapse. EMBO Molecular Med. 2014 May;6(5):640-650. http://embomolmed.embopress.org/content/6/5/640.long. Papa A, Wan L, Bonora M, Salmena L, Song MS, Hobbs RM, Lunardi A, Webster K, Ng C, Newton RH, Knoblauch N, Guarnerio J, et al. Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function. Cell. 2014 Apr 24;157(3):595-610. https://www.cell.com/cell/abstract/S0092-8674(14)00363-8. Schiering C, Guarnerio J, Basso V, Muzio L, Mondino A. Antigen-experienced CD4(+) T cells limit naïve T-cell priming in response to therapeutic vaccination in vivo. Cancer Res. 2010 Aug 1;70(15):6161-6170. https://aacrjournals.org/cancerres/article/70/15/6161/559504/Antigen-Experienced-CD4-T-Cells-Limit-Naive-T-Cell Caserta S, Alessi P, Guarnerio J, Basso, Mondino A. Synthetic CD4 T cell-targeted antigen-presenting cells elicit protective antitumor responses. Cancer Res. 2008 Apr 15;68(8):3010-3018. http://cancerres.aacrjournals.org/content/68/8/3010.long. Contact the Guarnerio Lab 8700 Beverly Blvd. Davis Building, Room 3027 Los Angeles, CA 90048 310-423-4971 Send a Message Please ensure Javascript is enabled for purposes of website accessibility