Publications - Gonsky Lab Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Gonsky Lab Back to Gonsky Lab Lab Members Publications Research Areas Publications See a complete PubMed list of publications by Rivkah Gonsky, PhD. Selected Key Publications Gonsky R, Fleshner P, Deem RL, Biener-Ramanujan E, Li D, Potdar AA, Bilsborough J, Yang S, McGovern DPB, Targan SR. Association of ribonuclease T2 gene polymorphisms with decreased expression and clinical characteristics of severity in Crohn's disease. Gastroenterology. 2017 Jul;153(1):219-232. https://www.gastrojournal.org/article/S0016-5085(17)35412-4/fulltext. Gonsky R, Deem RL, Landers CJ, Haritunians T, Yang S, Targan SR. IFNG rs1861494 polymorphism is associated with IBD disease severity and functional changes in both IFNG methylation and protein secretion. Inflamm Bowel Dis. 2014 Oct;20(10):1794-1801. https://academic.oup.com/ibdjournal/article/20/10/1794/4578865 Gonsky R, Deem RL, Targan SR. Multiple activating and repressive cis-promoter regions regulate TNFSF15 expression in human primary mononuclear cells. Cytokine. 2013 Jul;63(1):36-42. https://www.sciencedirect.com/science/article/pii/S104346661300152X. Gonsky R, Deem RL, Landers CJ, Derkowski CA, Berel D, McGovern DP, Targan SR. Distinct IFNG methylation in a subset of ulcerative colitis patients based on reactivity to microbial antigens. Inflamm Bowel Dis. 2011 Jan;17(1):171-178. https://academic.oup.com/ibdjournal/article/17/1/171/4631118 Biener-Ramanujan E, Gonsky R, Ko B, Targan SR. Functional signaling of membrane-bound TL1A induces IFN-gamma expression. FEBS Lett. 2010 Jun;584(11):2376-2380. http://onlinelibrary.wiley.com/doi/10.1016/j.febslet.2010.04.030. Shih DQ, Kwan LY, Chavez V, Cohavy O, Gonsky R, Chang EY, Chang C, Elson CO, Targan SR. Microbial induction of inflammatory bowel disease associated gene TL1A (TNFSF15) in antigen presenting cells. Eur J Immunol. 2009 Nov;39(11):3239-3250. http://onlinelibrary.wiley.com/doi/10.1002/eji.200839087/full. Gonsky R, Deem RL, Targan SR. Distinct methylation of IFNG in the gut. J Interferon Cytokine Res. 2009 Jul;29(7):407-414. http://online.liebertpub.com/doi/abs/10.1089/jir.2008.0109. Gonsky R, Deem RL, Bream JH, Young HA, Targan SR. An IFNG SNP with an estrogen-like response element selectively enhances promoter expression in peripheral but not lamina propria T cells. Genes Immun. 2006 Jul;7(5):342-351. https://www.nature.com/articles/6364305. Gonsky R, Deem RL, Bream J, Young HA, Targan SR. Enhancer role of STAT5 in CD2 activation of IFN-gamma gene expression. J Immunol. 2004 Nov 15;173(10):6241-6247. http://www.jimmunol.org/content/173/10/6241.long. Bream JH, Hodge DL, Gonsky R, Spolski R, Leonard WJ, Krebs S, Targan S, Morinobu A, O'Shea JJ, Young HA. A distal region in the interferon-gamma gene is a site of epigenetic remodeling and transcriptional regulation by interleukin-2. J Biol Chem. 2004 Sep 24;279(39):41249-41257. http://www.jbc.org/content/279/39/41249.long. Contact the Gonsky Lab 8700 Beverly Blvd. Davis Building, Room D4062 Los Angeles, CA 90048 310-423-7624 Send a Message Please ensure Javascript is enabled for purposes of website accessibility