Publications - Chung Lab Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Chung Lab Back to Chung Lab Lab Members Publications Research Areas Publications See a complete PubMed list of publications by Leland Chung, PhD. Selected Key Publications Shiao SL, Chu GC, Chung LW. Regulation of prostate cancer progression by the tumor microenvironment. Cancer Lett. 2016 Jan 28;pii: S0304-3835(15)00773-00779. http://www.cancerletters.info/article/S0304-3835(15)00773-9/abstract. Wu JB, Shi C, Chu GC, Xu Q, Zhang Y, Li Q, Yu JS, Zhau HE, Chung, LW. Near-infrared fluorescence heptamethine carbocyanine dyes mediate imaging and targeted drug delivery for human brain tumor. Biomaterials. 2015 Oct;67:1-10. http://www.sciencedirect.com/science/article/pii/S0142961215006109. Shi C, Wu JB, Chu GC, Li Q, Wang R, Zhang C, Zhang Y, Kim HL, Wang J, Zhau HE, Pan D, Chung LW. Heptamethine carbocyanine dye-mediated near-infrared imaging of canine and human cancers through the HIF-1α/OATPs signaling axis. Oncotarget. 2014;5(20):10114-10126. http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=2464&path[]=5033. Gururajan M, Josson S, Chu GC, Lu CL, Lu YT, Haga CL, Zhau HE, Liu C, Lichterman J, Duan P, Posadas EM, Chung LW. miR-154* and miR-379 in the DLK1-DIO3 microRNA mega-cluster regulate epithelial to mesenchymal transition and bone metastasis of prostate cancer. Clin Cancer Res. 2014;20(24):6559-6569. https://aacrjournals.org/clincancerres/article/20/24/6559/118042/miR-154-and-miR-379-in-the-DLK1-DIO3-MicroRNA-Mega Wu JB, Shao C, Li X, Li Q, Hu P, Shi C, Li Y, Chen YT, Yin F, Liao CP, Stiles BL, Zhau HE, Shih JC, Chung LW. Monoamine oxidase A mediates prostate tumorigenesis and cancer metastasis. J Clin Invest. 2014;124(7):2891-2908. https://www.jci.org/articles/view/70982. Chu G C-Y, Zhau HYE, Wang R, Rogatko A, Feng X, Zayzafoon M, Liu Y, Farach-Carson MC, You S, Kim J, Freeman MR, Chung LWK. RANK- and c-Met-mediated signal network amplification promotes prostate cancer metastatic colonization. Endocr Relat Cancer. 2014;21(2):311-326. https://erc.bioscientifica.com/view/journals/erc/21/2/311.xml. Josson S, Matsuoka Y, Gururajan M, Nomura T, Huang WC, Yang X, Lin JT, Bridgman R, Chu CY, Johnstone PA, Zayzafoon M, Hu P, Zhau H, Berel D, Rogatko A, Chung LW. Inhibition of β2-microglobulin/hemochromatosis enhances radiation sensitivity by induction of iron overload in prostate cancer cells. PLOS One. 2013;8(7):e68366. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0068366. Huang WC, Li X, Liu J, Lin J, Chung LW. Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells. Mol Cancer Res. 2012;10(1):133-142. https://aacrjournals.org/mcr/article/10/1/133/89136/Activation-of-Androgen-Receptor-Lipogenesis-and. Hu P, Chu GC, Zhu G, Yang H, Luthringer D, Prins G, Habib F, Wang Y, Wang R, Chung LW, Zhau HE. Multiplexed quantum dot labeling of activated c-Met signaling in castration-resistant human prostate cancer. PLOS One. 2011;6(12):e28670. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028670. Zhang S, Wang X, Osunkoya AO, Iqbal S, Chen Z, Muller S, Chen Z, Josson S, Coleman IM, Nelson PS, Wang YA, Wang RX, Shin DM, Marshall FF, Kucuk O, Chung LW, et al. EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis. Oncogene. 2011;30(50):4941-4952. http://www.nature.com/onc/journal/v30/n50/full/onc2011199a.html. Yang X, Shi C, Tong R, Qian W, Zhau HE, Wang R, Zhu G, Cheng J, Yang VW, Cheng T, Henary M, Strekowski L, Chung LW. Near IR heptamethine cyanine dye-mediated cancer imaging. Clin Cancer Res. 2010;16(10):2833-2844. https://aacrjournals.org/clincancerres/article/16/10/2833/75026/Near-IR-Heptamethine-Cyanine-Dye-Mediated-Cancer Huang WC, Zhau HE, Chung LW. Androgen receptor survival signaling is blocked by anti-beta2-microglobulin monoclonal antibody via a MAPK/lipogenic pathway in human prostate cancer cells. J Biol Chem. 2010;285(11):7947-7956. http://www.jbc.org/content/285/11/7947.long. Thalmann GN, Rhee H, Sikes RA, Pathak S, Multani A, Zhau HE, Marshall FF, Chung LW. Human prostate fibroblasts induce growth and confer castration resistance and metastatic potential in LNCaP cells. Eur Urol. 2010;58(1):162-171. http://www.sciencedirect.com/science/article/pii/S030228380900894X. Sung SY, Hsieh CL, Law A, Zhau HE, Pathak S, Multani AS, Lim S, Coleman IM, Wu LC, Figg WD, Dahut WL, Nelson P, Lee JK, Amin MB, Lyles R, Johnstone PA, Marshall FF, Chung LW. Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis. Cancer Res. 2008; 68(23):9996-10003. https://aacrjournals.org/cancerres/article/68/23/9996/540903/Coevolution-of-Prostate-Cancer-and-Bone-Stroma-in. Seo SI, Gera L, Zhau HE, Qian W-P, Iqbal S, Johnson NA, Zhang S, Zayzafoon M, Stewart J, Chung LW, Wu D. BKM1740, an acyl-tyrosine bisphosphonate amide derivative, inhibits the bone metastatic growth of human prostate cancer cells by inducing apoptosis. Clin Cancer Res. 2008;14(19):6198-6206. https://aacrjournals.org/clincancerres/article/14/19/6198/73087/BKM1740-an-Acyl-Tyrosine-Bisphosphonate-Amide Contact the Chung Lab 8750 Beverly Blvd. Atrium Building, Room 103 Los Angeles, CA 90048 Lab 310-423-5992 Office 310-423-8543 Send a Message Please ensure Javascript is enabled for purposes of website accessibility