Digestive Diseases Research Cores & Services Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Digestive Diseases Research Center Back to Digestive Diseases Research Center About Us Membership Research Themes Cores & Services Pilot & Feasibility Program Enrichment Program Events Publications Cores & Services The Cedars-Sinai Digestive Diseases Research Center's (CSDDRC) cores consist of the Administrative Core (Core A), the Advanced In Vitro Model Systems and Imaging Core (Core B), the Gnotobiotics and Gut Microbiome Core (Core C), and the Translational and Clinical Resources Core (Core D). The cores all leverage and build on Cedars-Sinai's strengths while providing access to unique resources. Administrative Core The Administrative Core integrates the CSDDRC's components into a cohesive entity. It facilitates collaboration between clinical and basic investigators through the provision of cutting-edge services and technologies by three biomedical research cores, access to a robust Enrichment Program, support for Pilot and Feasibility Program projects, and overall thematic direction. Contact Us About Our Services Advanced In Vitro Model Systems and Imaging Led by Drs. Ekihiro Seki and Robert Barrett, the Advanced In Vitro Model Systems and Imaging Core provides cutting-edge in vitro models as well as state-of-the-art microscopic imaging analyses to investigate specific metabolic, inflammatory, and fibrotic pathways and pathophysiology in intestine, liver and pancreatic disease. Key services include: Primary liver and pancreatic cells from rodents and humans iPSC-derived intestinal and pancreatic organoids Liver-, intestine- and pancreas-on-a-chip models 3D confocal microscopy imaging and GeoMX-DSP analysis CyTOF and imaging mass cytometry Contact Dr. Seki or Dr. Barrett for more information or to arrange services. Contact Us About Our Services Gnotobiotics and Gut Microbiome Led by Drs. David Underhill and Suzanne Devkota, the core provides tools for deep characterization of the gut microbiome and investigative strategies—including gnotobiotic animals and microbial culture and characterization technologies—to reveal the effects of microbiome in promoting specific pathways of inflammatory disease. Key services include: Microbiome sequencing and analysis service and support Aerobic and anaerobic microbial cultivation Gnotobiotic and germ-free mouse services Consultation on microbiome experimental design Contact Dr. Underhill or Dr. Devkota for more information or to arrange services. Contact Us About Our Services Translational and Clinical Resources Led by Drs. Jonathan Braun and Ju Dong Yang, the Translational and Clinical Resources Core provides the tools to facilitate the process of translating the role of inflammation in cell and animal models of digestive diseases to actual human biology. Key services include: Biospecimen collection and preprocessing service Archival biospecimen virtual repository service Large public datasets service State-of-the-art, high-throughput and highly quantitative proteomic and metabolomic analytic services Archival imaging virtual repository service Prestudy consultation service Contact Dr. Braun or Dr. Yang for more information or to arrange services. Contact Us About Our Services Have Questions or Need Help If you have questions or would like to learn more about the CSDDRC, please contact Shelly Lu, MD, or Stephen Pandol, MD. Davis Building, Room 2097 8700 Beverly Blvd. Los Angeles, CA 90048 Call 310-423-9031 Send A Message Please ensure Javascript is enabled for purposes of website accessibility