Movement Disorders Cedars-Sinai Skip to content Close Select your preferred language English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog English English عربى 简体中文 繁體中文 فارسي עִברִית 日本語 한국어 Русский Español Tagalog Translation is unavailable for Internet Explorer Cedars-Sinai Home 1-800-CEDARS-1 1-800-CEDARS-1 Close Find a Doctor Locations Programs & Services Health Library Patient & Visitors Community My CS-Link RESEARCH clear Go Close Navigation Links Academics Faculty Development Community Engagement Calendar Research Research Areas Research Labs Departments & Institutes Find Clinical Trials Research Cores Research Administration Basic Science Research Clinical & Translational Research Center (CTRC) Technology & Innovations News & Breakthroughs Education Graduate Medical Education Continuing Medical Education Graduate School of Biomedical Sciences Professional Training Programs Medical Students Campus Life Office of the Dean Simulation Center Medical Library Program in the History of Medicine About Us All Education Programs Departments & Institutes Faculty Directory Neurosciences Research Back to Neurosciences Research Current Research Alzheimer's Disease Brain Aneurysms Brain Tumor Human Neurophysiology Immunotherapy and Immunotherapy Vaccine Intraoperative Imaging Molecular Models of Tumors Movement Disorders Multiple Sclerosis Nanotechnology and Drug Delivery Neuromuscular Disorders Neurosurgical Outcomes Stroke Educational Opportunities Multidisciplinary Collaboration Research Team Neurosciences Laboratories Movement Disorders Preclinical Research Researchers are studying stem cell therapy as a potential treatment for Parkinson's. In experimental studies, we are investigating novel ways of using stem cells modified to release powerful growth factors to treat the disease. Principal Investigators: Michele Tagliati, MD, and Clive Svendsen, PhD Clinical Research Researchers continually pursue clinical trials to test new modalities of treatment for our patients. Our current trials include: Deep Brain Stimulation (DBS): Intrepid Vercise Device for Parkinson's Disease Istradefylline as Treatment for Parkinson's Disease Observational Longitudinal Studies Using short- and long-term evaluation of patients, we are broadening our efforts to learn how effectively patients react to treatment interventions and assessing potential precursors to disease. Deep Brain Stimulation As a pioneer in deep brain stimulation (DBS) management, our research aims to better understand the safety, reliability and effectiveness of the treatment in movement disorders. Our research involves evaluation of patients undergoing DBS treatment and their outcomes. These evaluations can provide researchers with information on long-term management of DBS treatment, such as patients' responses to stimulation, any adverse events, programming issues and medication changes leading to alterations in treatment outcomes. Additionally, we recently characterized the precise brain area stimulated by DBS to relieve dystonia. Using a computerized model known as a "volume of tissue activation" model, we can predict effective regions of stimulation in the globus pallidus of patients with primary dystonia, opening the way for programming guides that may greatly simplify clinical DBS programming for dystonia and suggest further insights to the pathophysiology of the disease. Principal Investigator: Michele Tagliati, MD Nonmotor Symptoms To assess potential precursors to Parkinson's disease, we are studying ways to identify nonmotor symptoms, such as losses of smell, constipation, sleep difficulties, anxiety and depression. By evaluating nonmotor symptoms as they manifest, our researchers hypothesize that we might be able to identify the root cause of the disease. Principal Investigator: Michele Tagliati, MD Collaborative Research Our movement disorders research brings together a team of scientists, neurologists, and neurosurgeons, as well as develops collaborations with other specialty areas. Our research also involves collaborations with other institutions, which currently include: Case Western Reserve University, Ohio King's College, London Instituto Nacional de Neurología y Neurocirugía, Mexico Please ensure Javascript is enabled for purposes of website accessibility