Consumer’s Guide to Biologics for Eosinophilic Esophagitis Everyday Health Menu NewslettersSearch Digestive Health The Consumer s Guide to Biologics for Eosinophilic Esophagitis Everything you need to know about the first FDA-approved treatment for eosinophilic esophagitis. By Maria MastersMedically Reviewed by Ira Daniel Breite, MD Reviewed: July 21, 2022 Medically Reviewed I n May 2022, the U.S. Food and Drug Administration (FDA) approved the use of the biologic medication dupilumab ( How Biologics Treat EoE 5 Essential Facts About Biologics for Eosinophilic Esophagitis 1 The U S Food and Drug Administration FDA has approved only one biologic to treat eosinophilic esophagitis EoE That drug, dupilumab, is sold under the brand name Dupixent. It is approved to treat EoE in adults and children older than 12. 2 Other biologics are being studied for the treatment of EoE In time, dupilumab may no longer stand alone for EoE, as there are several other biologics in the works, says 3 Biologics are injectable medications Some biologics are given intravenously (through a needle into a vein) and some by infusion at a clinic or other setting. The biologic approved for EoE is self-administered subcutaneously, into the layer of fat just beneath the surface of the skin. You give it to yourself using an injector pen that comes prefilled with the prescribed dose of medication, typically 300 milligrams. 4 Taking a biologic for EoE may help treat associated conditions Biologic drugs are approved to treat a wide range of chronic disorders, says 5 Biologics are considered safe but may cause some minor side effects Biologics, unlike conventional medications, are created using living cells rather than biochemicals and have a solid safety track record. They’ve been available in the United States for decades, and most people who take them have no serious problems, says Cash. Even so, no medication is without side effects. In people with EoE who take dupilumab, for example, the most common side effects include upper respiratory tract infections, cold sores, joint pain, and reactions around the injection site, such as soreness, itching, and redness. Save these facts for easy reference. Download Now When Is It Time to Try a Biologic for Eosinophilic Esophagitis There are no established guidelines for when a biologic like dupilumab should be prescribed for eosinophilic esophagitis (EoE), but it’s usually reserved for when first-line treatments aren’t working. In the case of EoE, these are typically Review this list with your doctor to help you decide if you’re ready for a biologic. Download Now 6 FAQs About Taking a Biologic for Eosinophilic Esophagitis If you’re considering trying a biologic, you’re likely wondering what taking it on an ongoing basis will be like. When you speak to your doctor, they can offer you personalized input on these common concerns. Keep these FAQs about biologics handy. Download Now Making the Decision to Take a Biologic for Eosinophilic Esophagitis Congratulations You’ve learned how biologics work and how they treat EoE. Next step: Figure out if this type of drug might be right for you. Self-Reflection Before your next doctor’s appointment, ask yourself these key questions:Are you satisfied with your current treatment?Has it improved your symptoms as much as you’d hoped?If you follow an elimination diet, are you satisfied with it?How would you rate your quality of life? For example, does EoE cause you to feel anxious or depressed? Does it interfere with your daily routine? Answer these questions to help you reflect on your current treatment plan. Download Now Doctor Discussion If you’ve recently been diagnosed with eosinophilic esophagitis or aren’t satisfied with your current treatment, you may want to consider taking a biologic. Here are a few questions you can bring with you to your next doctor’s appointment. Use them to help you guide the conversation and learn whether this medication may be right for you.Am I a good candidate for a biologic?What can I expect by taking this medication?How long will the medication take to work?What type of symptom relief can I expect?How long will I need to take a biologic?Are there any medications, supplements, or preexisting conditions that can interfere with this treatment?What else should I know before I try a biologic? Use this guide to start the conversation at your next doctor’s appointment. Download Now More in Eosinophilic Esophagitis Dealing With Dysphagia When You Have Eosinophilic Esophagitis 4 Natural Remedies for Reflux Due to Eosinophilic Esophagitis What to Know About Elimination Diets for Eosinophilic Esophagitis NEWSLETTERS Sign up for our Digestive Health Newsletter SubscribeBy subscribing you agree to the Terms of Use and Privacy Policy. Wellness inspired Wellness enabled FacebookTwitterInstagramPinterestYoutubeTikTok About Us Careers Editorial Policy Newsletters Meet Our Health Expert Network Privacy Policy Health News Accessibility Statement Terms of Use Contact Us Feedback Do Not Sell My Personal Information Popular Topics AdChoices NEWSLETTERS Get the best in health and wellness SubscribeBy subscribing you agree to the Terms of Use and Privacy Policy. A PROPERTY OF EHGLogo More From Everyday Health: Castle Connolly Top Doctors DailyOM Diabetes Daily Everyday Health Care Migraine Again 1996-2022 Everyday Health, Inc. Everyday Health is among the federally registered trademarks of Everyday Health, Inc. and may not be used by third parties without explicit permission. Badges Badges Badges