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Center for Individualized Medicine

Pharmacogenomics in Patient Care

Drug-gene testing is also called pharmacogenomics or pharmacogenetics. All terms characterize the study of how your genes affect your body's response to medications. The word "pharmacogenomics" is combined from the words "pharmacology" (the study of the uses and effects of medications) and "genomics" (the study of genes and their functions). Your body has thousands of genes that you inherited from your parents. Genes determine which characteristics you have, such as eye color and blood type. Some genes are responsible for how your body processes medications. Pharmacogenomic tests look for changes or variants in these genes that may determine whether a medication could be an effective treatment for you or whether you could have side effects to a specific medication. Patient Information: Pharmacogenomics - Finding the Right Medication for You (PDF) Pharmacogenomic testing is one tool that may help your health care team determine the best medication for you. Your team also considers other factors such as your age, lifestyle, other medications you are taking and your overall health when choosing the right treatment for you. Mayo Clinic supports various research and clinical initiatives to bring pharmacogenomic testing into clinical practice. Your health care team may review and recommend pharmacogenomic testing when needed to address a specific health concern. Mayo Clinic also offers predictive services, where pharmacogenomic testing may be ordered for future use.

Genomic Sequencing Animation

Genomic sequencing is a process for analyzing a sample of DNA taken from your blood. In the lab, technicians extract DNA and prepare it for sequencing.

Current limitations of pharmacogenomic tests

Current limitations of pharmacogenomic testing include: One single pharmacogenomic test cannot be used to determine how you will respond to all medications. Your health care team may order a pharmacogenomics panel that tests multiple genes to access how your body breaks down certain medications. Pharmacogenomic tests are not available for all medications. Because pharmacogenomic tests are available only for certain medications, your health care team determines if you need to have a pharmacogenomic test prior to beginning a specific treatment. There are currently no pharmacogenomic tests for aspirin.

Pharmacogenomics Animation

Pharmacogenomics investigates how variations in genes affect response to medications, using a patient's genetic profile to predict a drug's efficacy, guide dosage and improve patient safety. Pharmacogenomic testing helps clinicians predict which medications will most likely produce desired responses in different patients.

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Pharmacogenomics for Patients

Detailed information is available for patients regarding pharmacogenomics and the purpose and costs of drug-gene testing.

Pharmacogenomics for Medical Professionals

The Mayo Clinic Center for Individualized Medicine provides detailed pharmacogenomic testing information and resources for medical professionals.

Otros temas en investigación

Profesores de investigación Laboratorios de investigación Sedes principales Centros y programas Departamentos y divisiones Ensayos clínicos Consejo de revisión institucional Becas post-doctorado Puestos con becas para capacitación Publications . ART-20510031

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