Extracorporeal membrane oxygenation ECMO - Mayo Clinic

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Extracorporeal membrane oxygenation ECMO

Overview

In extracorporeal membrane oxygenation (ECMO), blood is pumped outside of your body to a heart-lung machine that removes carbon dioxide and sends oxygen-filled blood back to tissues in the body. Blood flows from the right side of the heart to the membrane oxygenator in the heart-lung machine, and then is rewarmed and sent back to the body. This method allows the blood to "bypass" the heart and lungs, allowing these organs to rest and heal. ECMO is used in critical care situations, when your heart and lungs need help so that you can heal. It may be used in care for COVID-19, ARDS and other infections.

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Why it s done

ECMO at Mayo Clinic

Our caring teams of professionals offer expert care to people who need ECMO. Learn more ECMO may be used to help people who are very ill with conditions of the heart and lungs, or who are waiting for or recovering from a heart transplant. It may be an option when other life support measures haven't worked. ECMO does not treat or cure a disease, but can help you when your body temporarily can't provide your tissues with enough oxygen. Some heart conditions in which ECMO may be used include: Heart attack (acute myocardial infarction) Heart muscle disease (decompensated cardiomyopathy) Inflammation of the heart muscle (myocarditis) Life-threatening response to infection (sepsis) Low body temperature (severe hypothermia) Post-transplant complications Shock caused by the heart not pumping enough blood (cardiogenic shock) Some lung (pulmonary) conditions in which ECMO may be used include: Acute respiratory distress syndrome (ARDS) Blockage in a pulmonary artery in the lungs (pulmonary embolism) Coronavirus disease 2019 (COVID-19) Defect in the diaphragm (congenital diaphragmatic hernia) Fetus inhales waste products in the womb (meconium aspiration) Flu (influenza) Hantavirus pulmonary syndrome High blood pressure in the lungs (pulmonary hypertension) Pneumonia Respiratory failure Trauma

Risks

The most common risks that may occur with ECMO include: Bleeding Blood clot (thromboembolism) Blood clotting disorder (coagulopathy) Infection Loss of blood in hands, feet or legs (limb ischemia) Seizures Stroke (part of the brain is damaged by loss of blood or by a blood vessel that bursts)

How you prepare

ECMO is used when life support is needed after surgery, or when you are very ill and your heart or lungs need help so that you can heal. Your doctor will decide when it may be helpful. If you need ECMO, your doctor and trained respiratory therapists will prepare you.

What you can expect

Your doctor will insert a thin, flexible tube (cannula) into a vein to draw out blood and a second tube into a vein or artery to return warmed blood with oxygen to your body. You will receive other medications, including sedation, to make you comfortable while receiving ECMO, and may not be able to talk during this time. Depending on your condition, ECMO can be used for a few days to a few weeks. The amount of time you receive ECMO depends on your condition. Your doctor will talk with you or your family about what to expect.

Results

The outcomes associated with ECMO depend upon the severity of the health condition that led to use of ECMO. Your doctor can explain how helpful ECMO may be in your situation.

Clinical trials

Explore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions. By Mayo Clinic Staff Extracorporeal membrane oxygenation ECMO care at Mayo Clinic Doctors & Departments April 19, 2022 Print Share on: FacebookTwitter Show references AskMayoExpert. Extracorporeal membrane oxygenation ECMO . Mayo Clinic; 2019. Office of Patient Education. Extracorporeal membrane oxygenation ECMO . Mayo Clinic; 2017. Office of Patient Education. Your child and ECMO. Mayo Clinic; 2018. Kalvelage EL (expert opinion). Mayo Clinic. April 2, 2020. Bohman JK (expert opinion). Mayo Clinic. April 9, 2020. Nasr DM, et al. Neurologic complications of extracorporeal membrane oxygenation. Journal of Clinical Neurology. 2015;11:383. Mehta H, et al. Indications and complications for VA-ECMO for cardiac failure. https://www.acc.org/latest-in-cardiology/articles/2015/07/14/09/27/indications-and-complications-for-va-ecmo-for-cardiac-failure. Accessed April 5, 2020. Makdisi G, et al. Extra corporeal membrane oxygenation (ECMO) review of a lifesaving technology. Journal of Thoracic Disease. 2015; doi:10.3978/j.issn.2072-1439.2015.07.17. Clinical management of severe acute respiratory infection when novel coronavirus (2019-nCoV) infection is suspected—interim guidance. World Health Organization. https://www.who.int/publications-detail/clinical-management-of-severe-acute-respiratory-infection-when-novel-coronavirus-(ncov)-infection-is-suspected. Accessed April 6, 2020. Ramanathan K, et al. Planning and provision of ECMO services for severe ARDS during the COVID-19 pandemic and other outbreaks of emerging infectious diseases. The Lancet Respiratory Medicine. 2020; doi:10.1016/S2213-2600(20)30121-1. Gray WS (expert opinion). Mayo Clinic. April 9, 2020.

ARDS Cardiogenic shock Cardiomyopathy Coronavirus disease 2019 (COVID-19) Hantavirus pulmonary syndrome Heart attack Hypothermia Influenza (flu) Multisystem inflammatory syndrome in children (MIS-C) Myocarditis Pneumonia Pulmonary embolism Pulmonary hypertension Sepsis Show more related content

News from Mayo Clinic

Mayo Clinic Q and A: What is extracorporeal membrane oxygenation? May 13, 2021, 05:30 p.m. CDT Sharing Mayo Clinic: Cared for in his own workplace for 121 days April 25, 2021, 10:48 p.m. CDT Young patient with COVID-19 recovering after hospital stay, ECMO support Feb. 18, 2021, 04:23 p.m. CDT Mom comes home after 4 months in the hospital with COVID-19 complications Nov. 15, 2020, 01:48 p.m. CDT Show more news from Mayo Clinic

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