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Calcium supplements Do they interfere with blood pressure drugs

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Is it true that calcium supplements may interact with blood pressure medications

Answer From Carrie Krieger, Pharm.D. Yes. In large amounts, calcium supplements may interact with some blood pressure medications. Interactions may occur with: Thiazide diuretics. These medications are also referred to as water pills. Taking large amounts of calcium with thiazide diuretics - such as chlorothiazide (Diuril), hydrochlorothiazide (Microzide) and indapamide - can increase the risk of milk-alkali syndrome, a serious condition. In general, avoid taking large amounts of calcium daily if you're taking a thiazide diuretic. This includes calcium supplements and calcium food sources. If you take calcium supplements while taking a thiazide diuretic, talk to your health care provider about the appropriate dose. Also ask to have your blood pressure and calcium levels checked. Calcium channel blockers. Supplemental calcium may decrease the effects of calcium channel blockers, such as nifedipine (Procardia), verapamil (Calan SR, Verelan), diltiazem (Cardizem, Cartia XT, others) and others. In fact, calcium is delivered through an IV line to help reverse a calcium channel blocker overdose. To be safe, check your blood pressure regularly if taking calcium channel blockers and calcium supplements at the same time. Calcium supplements don't appear to interact with other commonly prescribed blood pressure medications, such as: Angiotensin II receptor blockers, including losartan (Cozaar), valsartan (Diovan) and others Angiotensin-converting enzyme (ACE) inhibitors, including captopril, lisinopril (Zestril) and others Beta blockers, including carvedilol (Coreg) and metoprolol (Lopressor, Toprol-XL, Kapspargo Sprinkle) and others Renin inhibitors, including aliskiren (Tekturna) Talk to your care provider if you take high blood pressure medications and calcium supplements and are concerned about interactions. Depending on your specific medications, you may need to take a calcium supplement with or between meals. With Carrie Krieger, Pharm.D. There is a problem with information submitted for this request. Review/update the information highlighted below and resubmit the form.

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Blood pressure medications: Can they raise my triglycerides?Diuretics: A cause of low potassium? ShareTweet Aug. 27, 2022 Show references Calcium. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Dec. 28, 2020. Yu ASL, et al. The milk-alkali syndrome. https://www.uptodate.com/contents/search. Accessed Dec. 28, 2020. Bisoprolol. IBM Micromedex. https://www.micromedexsolutions.com. Accessed Dec. 28, 2020. Propranolol. IBM Micromedex. https://www.micromedexsolutions.com. Accessed Dec. 28, 2020. Captopril. IBM Micromedex. https://www.micromedexsolutions.com. Accessed Dec. 28, 2020. Lisinopril. IBM Micromedex. https://www.micromedexsolutions.com. Accessed Dec. 28, 2020. Losartan potassium. IBM Micromedex. https://www.micromedexsolutions.com. Accessed Dec. 28, 2020. Valsartan. IBM Micromedex. https://www.micromedexsolutions.com. Accessed Dec. 28, 2020. Aliskiren. IBM Micromedex. https://www.micromedexsolutions.com. Accessed Dec. 28, 2020. Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Elsevier; 2016. https://www.clinicalkey.com. Accessed Dec. 28, 2020. De Leon TV, et al. Potential dietary supplement and medication interactions in a subset of the older adult population attending congregate sites. Journal of Nutrition in Gerontology and Geriatrics. 2018; doi:10.1080/21551197.2018.1519481. Krieger CA (expert opinion). Mayo Clinic. Jan. 8, 2021. See more Expert Answers

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Calcium supplements Do they interfere with blood pressure drugs? Mayo Clinic