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Delta 8 vs Delta 9 vs Delta 10 — What s the Difference 

Medically reviewed by Dominique Fontaine, BSN, RN, HNB-BC, HWNC-BC — By Sian Ferguson on September 28, 2022Share on PinterestVictor Bordera/Stocksy UnitedCannabis plants contain dozens of different cannabinoids. These plant-based chemicals each have their own unique effects on the human body. Cannabidiol (CBD) is one such cannabinoid. Another commonly known cannabinoid is tetrahydrocannabinol (THC). When we refer to THC, we’re typically talking about delta 9 THC. However, there are other forms of THC out there. Delta 8 and delta 10 are found in trace amounts in cannabis plants. These cannabinoids have similar chemical structures to delta 9, but their effects can be slightly different.

What s the short answer

Delta 8, delta 9, and delta 10 are different THC forms. All three chemicals can make you feel intoxicated (in other words, high). A 2022 study that looked at US-based internet search queries found that people are becoming increasingly interested in delta 8 THC. Public interest in delta 8 was particularly high in states that restricted the use of cannabis, which suggests that delta 8’s popularity is increasing because people think it may be a legal alternative to delta 9.

Delta 8 explained

Although delta 8 is similar to delta 9 THC, it has a slightly different chemical structure. This difference in chemical structure might mean that it has different effects. Delta 8 naturally occurs in cannabis plants in small, small amounts. As such, delta 8 products are typically made by synthetically converting CBD or delta 9 THC into delta 8. Very little is known about the effects of synthetic cannabinoids. In 1973, a study looked at the differences between delta 8 and delta 9 THC. It found that delta 8 could have the following effects:visual distortionseuphoriarelaxationdifficulties with thinking and speaking More recently, a 2021 study surveyed delta 8 users. About half of people surveyed used delta 8 for medical reasons, specifically:panic attacksstressdepressionbipolar disorderchronic pain The study found that consumers felt that delta 8 was an effective substitute for delta 9 — in some cases, they felt that delta 8 had less intense side effects. Another 2022 study authored by the same researchers surveyed 521 delta 8 users, many of whom claimed that the side effects of delta 8 products were not as bad as that of regular cannabis. Anecdotally, delta 8 users on forums claim that delta 8 makes them sleepy and relaxed. Many people also claim that it stimulates appetite, a common effect of cannabis known as the “munchies.” As a 2022 paper explains, there’s a worrying lack of research into delta 8 THC. We don’t yet know its potential benefits and risks — and given that it’s fairly easy to buy, this is concerning.

Delta 9 explained

Delta 9 THC is the most abundant form of THC in cannabis plants. When you buy products that contain THC, you’re typically getting delta 9 THC. THC is perhaps most well-known for making people feel intoxicated, or high. However, it might also have health benefits. According to research, it might help with:anxietyglaucomainsomnialow appetitemuscle spasticityobstructive sleep apneanauseapain A synthetic form of delta 9 THC is used to create dronabinol (Marinol), a drug approved by the U.S. Food & Drug Administration (FDA) to stimulate appetite in people undergoing chemotherapy, people with HIV or AIDS, and people with anorexia.

Delta 10 explained

There is very little research on the benefits and side effects of delta 10. Anecdotally, delta 10 users claim that the high is mellow but energizing. People also claim that they feel more euphoric after consuming delta 10. However, because there’s a lack of research, there’s no proof to verify these claims.

Side effects risks and overall safety

Typical side effects of THC include:red eyesdry mouth (“cotton mouth”)increased appetite (“munchies”)difficulty thinking and speakingslowed reaction timesanxietyrapid heart ratememory loss The FDA has said that it received 104 reports of adverse events in people who used delta 8 products between December 1, 2020, and February 28, 2022. The reported adverse effects include:hallucinationsvomiting tremors anxiety dizziness confusion loss of consciousness A major issue with delta 8 and 10 products is that they are not regulated. This means that it’s difficult for consumers to figure out whether they’re buying legitimate, high quality products. There is no way to ensure that these products contain what manufacturers say they contain, or that they’re free from harmful contaminants.

Legality

Are delta 8 and delta 10 THC legal? The answer is complicated. At a federal level, delta 8 and delta 10 are technically legal. This is because the Farm Bill of 2018 made hemp legal to buy, sell, and grow. The bill defined hemp as a plant containing less than 0.3% of delta 9 THC by weight. Because the Farm Bill focuses explicitly on delta 9 and not delta 8 or 10, it’s a bit of a legal loophole: delta 8 and 10 products that are derived from hemp could fall into a legal gray zone. It’s more complicated than that, though. Because cannabis plants contain only trace amounts of delta 8 and delta 10, they’re usually made synthetically. Many states have laws against synthetic cannabinoids. Whether delta 8 and delta 10 are synthetic cannabinoids is debatable: both appear naturally in cannabis plants, but the legal definition of “synthetic cannabinoid” can be broad enough to include any cannabinoid that is made synthetically, including commercial delta 8 and 10 products. Both delta 8 and delta 10 are explicitly restricted in certain states. And, given the controversy around delta 8 and delta 10, it’s possible that lawmakers will soon introduce more state-level laws that restrict these cannabinoids. You can find out about your state’s laws by looking at the Norml.org map of cannabis-related legislation.

The bottom line

THC is the chemical in cannabis that is responsible for making you feel intoxicated. It can also have medical benefits. The THC found in cannabis plants is typically delta 9 THC. Thanks to a legal loophole in the 2018 Farm Bill, delta 8 and 10 THC are becoming increasingly popular. Although delta 8 and delta 10 THC can cause intoxication, they are less restricted in certain states. However, the safety and benefit of delta 8 and 10 remain to be seen. Both cannabinoids need to be studied further before we understand their potential side effects. Sian Ferguson is a freelance health and cannabis writer based in Cape Town, South Africa. She’s passionate about empowering readers to take care of their mental and physical health through science-based, empathetically delivered information. Last medically reviewed on September 28, 2022

How we vetted this article

SourcesHistoryHealthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.5 Things to Know about Delta-8 Tetrahydrocannabinol – Delta-8 THC. (2022).
fda.gov/consumers/consumer-updates/5-things-know-about-delta-8-tetrahydrocannabinol-delta-8-thcHollister MD, et al. (1973). Delta-8- and delta-9-tetrahydrocannabinol; Comparison in man by oral and intravenous administration.
ascpt.onlinelibrary.wiley.com/doi/10.1002/cpt1973143353Johnson-Arbor K, et al. (2022). The current state of delta-8 THC.
sciencedirect.com/science/article/abs/pii/S0735675721005520?via%3DihubKruger D, et al. (2021). Consumer Experiences with Delta-8-THC: Medical Use, Pharmaceutical Substitution, and Comparisons with Delta-9-THC.
liebertpub.com/doi/abs/10.1089/can.2021.0124Kruger D, et al. (2022). Delta-8-THC: Delta-9-THC's nicer younger sibling?
jcannabisresearch.biomedcentral.com/articles/10.1186/s42238-021-00115-8Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Current Version Sep 28, 2022 By Sian Ferguson Edited By Tess Catlett Medically Reviewed By Dominique Fontaine, BSN, RN, HNB-BC, HWNC-BC Copy Edited By Copy Editors Share this articleMedically reviewed by Dominique Fontaine, BSN, RN, HNB-BC, HWNC-BC — By Sian Ferguson on September 28, 2022

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