Mayo Clinic Department of Ophthalmology - Clinical trials - Mayo Clinic
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Clinical trials
Below are current clinical trials.
28 studies in Ophthalmology
(open studies only). Filter this list of studies by location, status and more. A Study to Evaluate Patient Reported Outcome Measures in Children with Eye Conditions
Rochester, Minn. The objectives of this study are: To evaluate patient-reported quality of life and functional vision across the spectrum of pediatric eye conditions; To assess change in patient-reported quality of life and functional vision over time; To compare the impact of different treatments on quality of life and functional vision; To assess change in patient-reported quality of life and functional vision in response to treatment; To determine associations between quality of life / functional vision scores and specific clinical and demographic characteristics. A Study to Evaluate Advanced Ultrasound Techniques for Diagnosis of Giant Cell Arteritis
Rochester, Minn. The purpose of this study is to find out if advanced ultrasound studies can be used to make a diagnosis of giant cell arteritis. Ultimately, we hope to be able to offer non-invasive diagnostic options as an alternative to biopsy to future patients who are being evaluated for giant cell arteritis. A Study to Evaluate the Effectiveness of Critical Flicker Fusion in Distinguishing Different Causes of Altered Vision
Rochester, Minn. The purpose of this study is to evaluate the effectiveness of the critical flicker fusion device in distinguishing different kinds of optic neuropathy and visual perception. A Study to Evaluate a Color Test for Patients with Optic Nerve Diseases
Rochester, Minn. The purpose of this study is to evaluate the clinical utility of a quantitative test to measure how color saturation appears in patients with diseases of the optive nerve. Exparel Injection for Postoperative Orbital Pain
Rochester, Minn. After surgery to remove the eye, either by enucleation or evisceration, patients have variable levels of pain for several postoperative days. Some patients have almost no discomfort while others require significant amounts of oral narcotics and report pain of 10 out of 10 on a numerical rating scale. The current operative standard is to infiltrate the eye socket with 0.5% bupivacaine during surgery leading to several hours of postoperative analgesia. In 2011, Pacira Pharmaceuticals released a bupivacaine liposomal injectable suspension (Exparel, 1.3%) which offers sustained release of bupivacaine giving postoperative pain control for up to 72 hours. This medication has been used in numerous surgeries including inguinal hernia repair, hemorrhoidectomy, bunionectomy, breast reconstruction, and orthopedic surgery, and the literature reports improved pain control, decreased use of oral opioids, and increased patient satisfaction. There are no reports of the use of Exparel in the ophthalmic literature. The investigators propose a randomized, controlled trial to compare the postoperative pain control offered by sustained release bupivacaine to that offered by standard plain bupivacaine after enucleation or evisceration. A Study Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles Plus Patching for Amblyopia in Children 3 to < 13 Years Old
Rochester, Minn. The purpose of this study is to determine whether simultaneous treatment with spectacles and patching has an equivalent VA outcome compared with sequential treatment, first with spectacles alone, followed by patching (if needed), for previously untreated amblyopia in children 3 to < 13 years of age. Intraocular Pressure in Ocular Hypertensives with Scleral Lens Wear
Rochester, Minn. The purpose of this study is to determine if short-term wear of a scleral contact lens will raise intraocular pressure in ocular hypertensive patients. A Study to Evaluate Optical Coherence Tomography OCT and OCT Angiography OCTA Imaging In Supine Patient
Rochester, Minn. The purpose of this study is to determine if a relay lens and right angle mirror can be used in conjunction with an FDA-approved optical coherence tomography (OCT) unit to allow imaging in supine patients. A Study to Evaluate Visual Function in Fuchs Endothelial Corneal Dystrophy
Rochester, Minn. The purpose of this study is to determine visual function in patients with Fuchs Endothelial Corneal Dystrophy (FECD) to understand when in the course of disease patients are affected by compromised vision. A Study to Compare Circadian Phase in Patients with Wet Macular Degeneration to Controls Without Ocular Pathology
Jacksonville, Fla. The purpose of this study is to determine if macular degeneration patients have a shift in their circadian rhythm due to pathology within the macula compared to patients without macular pathology. Request an Appointment at Mayo Clinic Locations, travel & lodgingResearch Oct. 11, 2022 Share on: FacebookTwitter Ophthalmology
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