Anesthesiology and Perioperative Medicine - Clinical trials - Mayo Clinic

COVID-19 Advice updates and vaccine options

Find out about COVID-19, COVID-19 vaccines, and Mayo Clinic patient and visitor updates. Skip to site navigation Skip to Content This content does not have an English version.This content does not have an Arabic version. Search Request an Appointment Find a Doctor Find a Job Give Now Log in to Patient Account English Español العربية 简体中文 Twitter Facebook Pinterest YouTube Menu Departments & Centers Medical Departments & Centers

Anesthesiology and Perioperative Medicine

Clinical trials

Below are current clinical trials.
30 studies in Anesthesiology and Perioperative Medicine
(open studies only). Filter this list of studies by location, status and more.

A Study to Evaluate Prevalence of Hypogonadism in Patients with Chronic Pain

Jacksonville, Fla. The purpose of this study is to evaluate the hormonal profile related to opioid-induced hypogonadism (OIH) in chronic pain patients before and after completing 3 weeks Interdisciplinary Pain Rehabilitation Program (IPRP) at Pain Rehabilitation Center (PRC) at Mayo Clinic/Florida.

A Study to Evaluate Unintended Prolonged Opioid Use

Rochester, Minn. The primary purpose of this study is to identify patient characteristics that are associated with unintended prolonged opioid use (UPUO).

A Study About Comparing a New Test of Blood Clotting with Standard Tests of Blood Clotting in Patients Who are Undergoing Heart Surgery

Rochester, Minn. The purpose of this study is to determine the correlation of the MCTS - CT with standard coagulation tests and coagulation factor levels.

Study to Evaluate the Effects of Vitamin B3 Derivative on Bone Skeletal Muscle and Metabolic Functions in Aging

Rochester, Minn. The purpose of this study is to evaluate the effects of vitamin B3 derivative on bone, skeletal, muscle and metabolic functions in aging.

Exparel Injection for Postoperative Orbital Pain

Rochester, Minn. After surgery to remove the eye, either by enucleation or evisceration, patients have variable levels of pain for several postoperative days. Some patients have almost no discomfort while others require significant amounts of oral narcotics and report pain of 10 out of 10 on a numerical rating scale. The current operative standard is to infiltrate the eye socket with 0.5% bupivacaine during surgery leading to several hours of postoperative analgesia. In 2011, Pacira Pharmaceuticals released a bupivacaine liposomal injectable suspension (Exparel, 1.3%) which offers sustained release of bupivacaine giving postoperative pain control for up to 72 hours. This medication has been used in numerous surgeries including inguinal hernia repair, hemorrhoidectomy, bunionectomy, breast reconstruction, and orthopedic surgery, and the literature reports improved pain control, decreased use of oral opioids, and increased patient satisfaction. There are no reports of the use of Exparel in the ophthalmic literature. The investigators propose a randomized, controlled trial to compare the postoperative pain control offered by sustained release bupivacaine to that offered by standard plain bupivacaine after enucleation or evisceration.

A Study to Evaluate Ultrasound-guided Erector Spinae Plane Blocks

Rochester, Minn. The purpose of this study is to to demonstrate the feasibility of performing ultrasound-guided erector spinae plane blocks in the Emergency Department (ED) and Intensive Care Unit (ICU).

A Study to Analyze the Effects of Buprenorphine on Hyperalgesia in Patients with Opioid Use Disorder

Rochester, Minn. The purpose of this study is to investigate the effects of buprenorphine on hyperalgesia (HP) perception in adults undergoing treatment for opioid use disorder (OUD).

Chronic Pain Biobank

Jacksonville, Fla. The purpose of this study is to create a biorepository for samples of chronic pain patients.

A Study to Analyze the Effects of Exparel for Post-Surgery Pain Control in Patients Undergoing Penile Prosthesis Placement

Rochester, Minn. The purpose of this study is to determine the effects of liposomal bupivacaine vs lidocaine/bupivacaine mixture in patients’ undergoing surgical placement of a penile prosthesis.

Tobacco Dependence Intervention Knowledge Practices and Attitudes among Registered Nurses

Rochester, Minn. The specific aim of this study is to determine if the implementation of a tobacco dependence intervention, among registered nurses on Gonda 7 caring for ambulatory surgical patients, results in a change in the knowledge, practices, and attitudes of patient tobacco use assessment as compared to baseline. Expertise & rankingsResearch March 30, 2021 Share on: FacebookTwitter