Hematology Clinical trials Mayo Clinic

Hematology Clinical trials Mayo Clinic

Hematology - Clinical trials - Mayo Clinic

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Hematology

Clinical trials

Below are current clinical trials.
150 studies in Hematology
(open studies only). Filter this list of studies by location, status and more.

In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells

Rochester, Minn. This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach

A Study to Evaluate Performance of Coagulation Laboratory Testing in Children and Young Adults

Rochester, Minn. The primary purpose of this study is to generate pediatric-specific reference ranges that take into account patient sex, age, corrected gestational age, ethnicity, etc., and laboratory variables for various coagulation studies.

Cutaneous Lymphoma Database

Scottsdale/Phoenix, Ariz. The purpose of this study is to create a long-term, prospective database of cutaneous lymphoma that will lead to a better understanding of the biological behavior of cutaneous lymphomas as well as the effectiveness of interventions.

A Study to Evaluate Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia

Rochester, Minn., Jacksonville, Fla. The purpose of this study is to compare the effectiveness of gilteritinib to midostaurin in patients receiving standard combination chemotherapy for FLT3 AML.

A Study to Collect Data and Blood Samples from Mayo Patients Who Have or are Suspected of Having Amyloidosis or Their Family Members for Future Research

Rochester, Minn. The purpose of this study is to create a data collection and bioregistry of blood samples from Mayo Clinic patients with amyloidosis, suspected amyloidosis, and family members of patients with amyloidosis. This information will be available for future research about this spectrum of diseases.

Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

Jacksonville, Fla., Rochester, Minn., Scottsdale/Phoenix, Ariz. This screening and multi-sub-study Phase 1b/2 trial will establish a method for genomic screening followed by assigning and accruing simultaneously to a multi-study "Master Protocol (BAML-16-001-M1)." The specific subtype of acute myeloid leukemia will determine which sub-study, within this protocol, a participant will be assigned to evaluate investigational therapies or combinations with the ultimate goal of advancing new targeted therapies for approval. The study also includes a marker negative sub-study which will include all screened patients not eligible for any of the biomarker-driven sub-studies.

Dose-Escalation Study of cevostamab BFCR4350A in Participants With Relapsed or Refractory Multiple Myeloma R R MM

Scottsdale/Phoenix, Ariz. This is a phase I, multicenter, open-label, dose-escalation study of cevostamab (BFCR4350A) administered as a single agent by IV infusion to participants with relapsed or refractory multiple myeloma (R/R MM).

A Study of WVT078 in Patients With Multiple Myeloma

Rochester, Minn. The purpose of this study is to establish a safe and tolerated dose of single agent WVT078 in patients with relapsed and/or refractory Multiple Myeloma (MM).

CC-220-MM-001 A Phase 1b 2a Multicenter Open-Label Dose-Escalation Study to Determine the Maximum Tolerated Dose Assess the Safety Tolerability Pharmacokinetics and Efficacy of CC-220 as Monotherapy and in Combination with Other Treatments in Subjects with Multiple Myeloma

Scottsdale/Phoenix, Ariz. This is a multicenter, multicountry, open-label, Phase 1b/2a dose-escalation study to determine the maximum tolerated dose of CC-220 when administered as monotherapy and in combination with dexamethasone. The study will consist of an escalating dose-escalation portion (Part 1) as well as an expansion of each cohort (ie, Cohort C: Monotherapy (MonoT) and Cohort D: Combination treatment with 2 drugs (DoubleT) at the recommended Phase 2 dose (RP2D) to further evaluate safety and estimate preliminary efficacy (Part 2).

A Study to Determine the Effects of Activity by Ambulation in Hospital Premises versus Strict Protective Isolation on Quality of Life in Severely Neutropenic Cancer Patients during Hospitalization

Jacksonville, Fla. The purpose of this study is to determine if allowing patients to ambulate in the hallways outside of their hospital room by relaxing the policy of strict protective isolation in neutropenic patients improves the quality of life, and if this increases the risk of infection among these patients during hospitalization. Request an Appointment at Mayo Clinic Locations, travel & lodgingResearch Oct. 11, 2022 Share on: FacebookTwitter

Hematology

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